The information of Sodium hyaluronate (CAS 9067-32-7)


NAME Sodium hyaluronate (HA)
CAS NO. 9067-32-7
MF (C14H20NO11Na) n
MW (401.3) n
Hazard Status None-dangerous chemical


Chemical properties:

Appearance white powder
PH 6.0-7.5
Transparency ≥99.0%
Loss on drying ≤10.0%
Limiting viscosity 17.3 to 27.2 dL/g
Protein ≤0.05%
Heavy metals ≤20 ppm
Glucuronic acid ≥45.0%
HA content ≥93.0%
Bacteria counts <10 cfu / g
Mold & Yeast <10 cfu / g


Injection Grade:
Intra-articular injection of sodium hyaluronate has been widely used in the treatment of osteoarthritis. Sodium hyaluronate is a large linear glycosaminoglycan composition of repeating disaccharide units of glucuronic acid and N-acetylglucosamine, linked via the 1-4 members of the sugar rings, It is one of the important components of cartilage matrix and has a protective effect on the progression of osteoarthritis. Sodium hyaluronate is also reported to inhibit the expression of MMP-1 and MMP-3 induced by interleukin-1β, and reduce cartilage degradation induced by Neutrophil leukocytes.

Sodium hyaluronate (High molecular weight) can form a thin permeable layer, It could help the skin lock the water. In the meantime, it protect protect the skinf from hurting by dust, bacteria,
Sodium hyaluronate (Low molecular weight) shows great property in penetrating into corium, inflated blood capillaries, promoting blood circulation, stimulating the cells nourishment. So it could diminishe the wrinkles, boost the skin elasticity and finally delay the skin aging process.
Sodium hyaluronate should be the best thicker and water retainer in personal care area. It shows great compatibility and stability. Thus it is widely applicated to skin care and cosmetic products, such as cream, lotion, astringent, essence, facial cleanser, shower gel, Shampoo, hair conditioner, mouse and lip sticker, etc.

Food Grade:
Lt; / RTI & Skin will look like coarse and wrinkled. Some diseases would appear when the HA decreasing, such as arthritis, arteriosclerosis, plus disorder and brain atrophy, etc. But the skin could be mosit, smooth and soft by digesting and absorbing HA, which could also Prevent the arthritis, arteriosclerosis, plus disorder and brain atrophy. It is efficient to replenish the best HA in body by orally taking HA skin-care and health-care food. And it shows great effect on activating the skin cells and improving the appearance of the Skin, to prevent aging and keep the health of aged people. In addition, it can make up body for the cosmetic products which are externally used.

Eyedrop Grade:
Sodium hyaluronate is the main component of connective tissue. As macromolecules, glycosaminoglycans distribute in the interstitial cells of various tissues and exert physiological functions such as cell adhesion and osmotic pressure regulation. Hyaluronic acid can be used as a viscoelastic agent in ophthalmic surgery. A 3% HA solution is highly viscoelastic, the operation is injected into the anterior chamber, which can effectively support the coating on the surface of the anterior chamber, and surgical instruments in ocular houses formed on the surface of the protective film, can avoid the Equipment damage. HA solution has the effect of stabilizing tear film.


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